Research
We use an integrative analysis of histone modifications, DNA methylation and expression of RNAs to understand gene regulation through epigenetic mechanisms.
We are interested in how stem cell states are defined and regulated. Stem and progenitor cells have to the unique ability to give rise to other cells in the human body. However, these cells have the same genetic make up as their differentiated daughter cells. We would like to understand how "stemness" is defined and how the epigenome contributes to the developmental plasticity of these cells.
We are interested in how stem cell states are defined and regulated. Stem and progenitor cells have to the unique ability to give rise to other cells in the human body. However, these cells have the same genetic make up as their differentiated daughter cells. We would like to understand how "stemness" is defined and how the epigenome contributes to the developmental plasticity of these cells.
